How does PREVYMIS work?

PREVYMIS helps keep people from getting sick from cytomegalovirus (CMV) by preventing the virus from multiplying.

How to take PREVYMIS

PREVYMIS comes as a tablet or can be given by your healthcare provider through an IV line (intravenously).

If you take PREVYMIS tablets:

  • Take PREVYMIS exactly as your healthcare provider tells you to take it. Do not stop taking PREVYMIS without talking to your healthcare provider first.
  • Take 1 PREVYMIS tablet 1 time each day.
  • Take PREVYMIS with or without food.
  • Swallow PREVYMIS tablets whole.
  • It is important that you do not miss or skip doses of PREVYMIS.
  • Store PREVYMIS tablets at room temperature between 68°F to 77°F (20°C to 25°C) in the original package until use.

If you forget to take the tablets:

  • If you miss a dose, take it as soon as you remember. If you do not remember until it is time for your next dose, skip the missed dose and take your dose at the next scheduled time. Do not take 2 doses of PREVYMIS at the same time or take more than your prescribed dose to make up for a missed dose.

If you receive PREVYMIS through an IV line (intravenously):

  • You will receive PREVYMIS 1 time each day, given over 1 hour.
  • If you miss or skip your dose of PREVYMIS, call your healthcare provider right away.

If you take too much PREVYMIS, call your healthcare provider right away.

Learn about CMV

Understanding CMV

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What is PREVYMIS® (letermovir)?

PREVYMIS is a prescription medicine used to help prevent:

  • Cytomegalovirus (CMV) infection and disease in adults who have received an allogeneic hematopoietic stem cell (bone marrow) transplant and who have a high risk for getting CMV infection and disease.
  • CMV disease in adults who have received a kidney transplant and who have a high risk for getting CMV disease.

It is not known if PREVYMIS is safe and effective in children under 18 years of age.

Important Safety Information

Do not take PREVYMIS if you take pimozide or ergot alkaloids.

 

If you are taking PREVYMIS with cyclosporine, do not take pitavastatin or simvastatin.

 

Before taking PREVYMIS, tell your healthcare provider about all your medical conditions, including if you have kidney or liver problems; are pregnant or plan to become pregnant, since it is not known if PREVYMIS will harm your unborn baby; and if you are breastfeeding or plan to breastfeed, since it is not known if PREVYMIS passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby while taking PREVYMIS.

 

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. PREVYMIS may affect the way other medicines work, and other medicines may affect how PREVYMIS works and can cause serious side effects.

 

Know the medicines you take. Keep a list of medicines and show it to your healthcare provider and pharmacist when you get a new medicine. Your healthcare provider or pharmacist will tell you if it is safe to take PREVYMIS with other medicines. Do not start or stop taking another medicine without telling your healthcare provider first.

 

The most common side effects of PREVYMIS in adults who have received a hematopoietic stem cell transplant include: nausea, diarrhea, vomiting, swelling in your arms and legs, cough, headache, tiredness, and stomach (abdominal) pain.

 

The most common side effect of PREVYMIS in adults who have received a kidney transplant is diarrhea.

 

These are not all the possible side effects of PREVYMIS.

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

 

Please read the accompanying Patient Information for PREVYMIS, and discuss it with your healthcare professional.

 

The Physician Prescribing Information also is available.

What is PREVYMIS® (letermovir)?

PREVYMIS is a prescription medicine used to help prevent:

  • Cytomegalovirus (CMV) infection and disease in adults who have received an allogeneic hematopoietic stem cell (bone marrow) transplant and who have a high risk for getting CMV infection and disease.
  • CMV disease in adults who have received a kidney transplant and who have a high risk for getting CMV disease.

It is not known if PREVYMIS is safe and effective in children under 18 years of age.

PREVYMIS is a prescription medicine used to help prevent:

  • Cytomegalovirus (CMV) infection and disease in adults who have received an allogeneic

PREVYMIS is a prescription medicine used to help prevent:

  • Cytomegalovirus (CMV) infection and disease in adults who have received an allogeneic hematopoietic stem cell (bone marrow) transplant and who have a high risk for getting CMV infection and disease.
  • CMV disease in adults who have received a kidney transplant and who have a high risk for getting CMV disease.

Important Safety Information for PREVYMIS® (letermovir)

Do not take PREVYMIS if you take pimozide or ergot alkaloids.

 

If you are taking PREVYMIS with cyclosporine, do not take pitavastatin or simvastatin.

 

Before taking PREVYMIS, tell your healthcare provider about all your medical conditions, including if you have kidney or liver problems; are pregnant or plan to become pregnant, since it is not known if PREVYMIS will harm your unborn baby; and if you are breastfeeding or plan to breastfeed, since it is not known if PREVYMIS passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby while taking PREVYMIS.

 

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. PREVYMIS may affect the way other medicines work, and other medicines may affect how PREVYMIS works and can cause serious side effects.

 

Know the medicines you take. Keep a list of medicines and show it to your healthcare provider and pharmacist when you get a new medicine. Your healthcare provider or pharmacist will tell you if it is safe to take PREVYMIS with other medicines. Do not start or stop taking another medicine without telling your healthcare provider first.

 

The most common side effects of PREVYMIS in adults who have received a hematopoietic stem cell transplant include: nausea, diarrhea, vomiting, swelling in your arms and legs, cough, headache, tiredness, and stomach (abdominal) pain.

 

The most common side effect of PREVYMIS in adults who have received a kidney transplant is diarrhea.

 

These are not all the possible side effects of PREVYMIS.

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

 

Please read the accompanying Patient Information for PREVYMIS, and discuss it with your healthcare professional.

 

The Physician Prescribing Information also is available.

Do not take PREVYMIS if you take pimozide or ergot alkaloids.

Do not take PREVYMIS if you take pimozide or ergot alkaloids.

If you are taking PREVYMIS with cyclosporine, do not take pitavastatin or simvastatin.

Before taking PREVYMIS, tell your healthcare provider about all your medical conditions, including if you have kidney or liver problems; are pregnant or plan